Dolz C, Raurich J M, Ibáñez J, Riera J, Marsé P, Obrador A
Sección Aparato Digestivo, Hospital Joan March, Palma de Mallorca, España.
Nutr Hosp. 1995 Mar-Apr;10(2):81-6.
In Crohn's disease, weight loss and malnutrition are very frequently occurring problems. One explanation of these findings could be an increased energy expenditure. Eleven patients were studied, of which six were women and five were men, during a hospital stay for an active episode of Crohn's disease. In three patients the small intestine was affected, in five the colon, and in the last three both the ileum and the colon were affected. Van Hees' activity index on admittance was 196 +/- 52 (132-265). The energy expenditure at rest (ECR) on admittance, was 11% higher than that found in the normal population (p: n.s.). The energy expenditure decreased weekly, in a statistically significant way, during hospitalization. No significant relationship was found between the Van Hees activity index and any of the parameters used to evaluate the energy needs. Those patients whose body weight was less than 90% of the ideal body weight, presented pathologically elevated energy needs when the energy expenditure was expressed in kcal/kg (p = 0.003). Fever was the only analyzed parameter which showed a significant correlation with the changes in energy expenditure: measured by the oxygen consumption index (p = 0.003) and by the percentage of REE (p = 0.006).
在克罗恩病中，体重减轻和营养不良是非常常见的问题。对这些发现的一种解释可能是能量消耗增加。对11名患者进行了研究，其中6名女性，5名男性，他们因克罗恩病的活动期而住院。3名患者的小肠受到影响，5名患者的结肠受到影响，最后3名患者的回肠和结肠均受到影响。入院时的范赫斯活动指数为196±52（132 - 265）。入院时的静息能量消耗（ECR）比正常人群高11%（p：无统计学意义）。住院期间，能量消耗每周以统计学显著的方式下降。未发现范赫斯活动指数与用于评估能量需求的任何参数之间存在显著关系。当以千卡/千克表示能量消耗时，那些体重低于理想体重90%的患者表现出病理性升高的能量需求（p = 0.003）。发热是唯一分析的与能量消耗变化呈显著相关的参数：通过耗氧指数测量（p = 0.003）和通过REE百分比测量（p = 0.006）。
