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母亲使用哌替啶对婴儿正在形成的母乳喂养行为的影响。

Effects of maternal pethidine on infants' developing breast feeding behaviour.

作者信息

Nissen E, Lilja G, Matthiesen A S, Ransjö-Arvidsson A B, Uvnäs-Moberg K, Widström A M

机构信息

Department of Woman and Child Health, Karolinska Hospital, Karolinska Institute, Stockholm, Sweden.

出版信息

Acta Paediatr. 1995 Feb;84(2):140-5. doi: 10.1111/j.1651-2227.1995.tb13596.x.

Abstract

The aim of this quasi-experimental study was to examine the effects of maternal pethidine during labour on the developing breast feeding behaviour in infants in the first 2 h after birth compared with infants not exposed to pethidine. Forty-four healthy infants were observed immediately after birth. They were placed skin-to-skin on their mothers' chests. The development of mouth and sucking movements as well as rooting behaviour and state of sleep/wakefulness were noted. The observer was blind as to the pain relief the mother had received during labour. Of the 44 mothers 18 had received pethidine. The main findings were that infants exposed to pethidine had delayed and depressed sucking and rooting behaviour. In addition, a smaller proportion of infants exposed to pethidine started to suckle the breast. Rooting movements which are expected to be vigorous at 30 min after birth were affected both by administration of pethidine and a longer second stage of labour. It is suggested that the differences found in sucking behaviour may be a central effect of pethidine. Depression of rooting movements in the pethidine group may be caused by exhaustion due to a longer second stage of labour and administration of pethidine. It is recommended that pethidine-exposed mother-infant couples stay together after birth long enough to enable the infant to make the choice to attach or not to attach to the nipple without the forceful helping hand of the health staff.

摘要

这项准实验研究的目的是,与未接触哌替啶的婴儿相比,研究产妇分娩时使用哌替啶对出生后2小时内婴儿母乳喂养行为发育的影响。44名健康婴儿在出生后立即接受观察。他们被母婴皮肤接触地放在母亲胸前。记录口部和吸吮动作的发育情况以及觅食行为和睡眠/觉醒状态。观察者对母亲在分娩时所接受的止痛措施不知情。44名母亲中,18名使用了哌替啶。主要研究结果是,接触哌替啶的婴儿吸吮和觅食行为延迟且受到抑制。此外,接触哌替啶的婴儿开始吸吮乳房的比例较小。预计出生后30分钟时活跃的觅食动作,受到哌替啶的使用和第二产程延长的影响。研究表明,在吸吮行为中发现的差异可能是哌替啶的中枢效应。哌替啶组觅食动作受抑制可能是由于第二产程延长和使用哌替啶导致的疲惫所致。建议接触过哌替啶的母婴在出生后长时间待在一起,以便婴儿能够在没有医护人员强行协助的情况下自主选择是否衔乳。

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