[Effect of entopeduncular nucleus and reticular part of substantia nigra on the antiepileptic activity of the caudate nucleus in the neocortex].

Experiments carried out on rats show that inhibiting influences from striatal electrostimulation on the cortical epileptic activity are removed under conditions of destruction of entopeduncular nucleus (EPN). They decrease under conditions of lesion of substantia nigra pars retieulata (SNR). It is found that both EPN and SNR destruction resulted in antiepileptic effect on the development of the neocortex epileptic activity complexes. Possible mechanisms realizing inhibition of the caudate nucleus effects on the neocortex epileptic activity are discussed.