Alánt O, Flautner L, Bock G Y, Mérei J
Acta Chir Acad Sci Hung. 1975;16(2):123-30.
Blood coagulation was studied in the course of 11 pancreatectomies and 7 pancreas transplantations. Comparison of the postoperative changes in the fibrinogen level suggests the important role of the normal pancreas in fibrinogen generation. Investigation of the indices of the coagulation and fibrinolytic system revealed in the post-transplantation period a shift in the activity of the coagulation indices towards hypercoagulability. The increased fibrinogen level, the inhibited fibrinolysis and the elevated activity of the coagulation factors are assumed to be responsible for the high incidence of thrombotic complications associated with transplantation of the pancreas.
在11例胰腺切除术和7例胰腺移植手术过程中对血液凝固进行了研究。纤维蛋白原水平术后变化的比较表明正常胰腺在纤维蛋白原生成中具有重要作用。对凝血和纤溶系统指标的研究显示，在移植后阶段，凝血指标活性向高凝状态转变。纤维蛋白原水平升高、纤溶受抑制以及凝血因子活性增强被认为是胰腺移植相关血栓并发症高发的原因。
