慢性淋巴细胞白血病患者体内和体外有丝分裂原反应性淋巴细胞的选择
In vivo and in vitro selection of mitogen responsive lymphocytes in patients with chronic lymphocytic leukemia.
作者信息
Blomgren H, Jondal M, Johansson B
出版信息
Acta Radiol Ther Phys Biol. 1976 Feb;15(1):23-32. doi: 10.3109/02841867609132705.
PMID:775891
Abstract
The in vitro mitogen response of blood lymphoid cells from patients with chronic lymphocytic leukemia was observed to be low compared to lymphocytes from healthy subjects. However, highly responsive cells could be separated from the blood of such patients by a buoyant density centrifugation technique and such reactive cells were found to be enriched by treating the patients with chemotherapy or splenic irradiation.
摘要
据观察，与健康受试者的淋巴细胞相比，慢性淋巴细胞白血病患者血液淋巴样细胞的体外有丝分裂原反应较低。然而，通过浮力密度离心技术可从这类患者的血液中分离出高反应性细胞，并且发现通过对患者进行化疗或脾脏照射，这类反应性细胞会增多。
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