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人类编码螺旋-环-螺旋蛋白的Id2A基因5'-侧翼区序列，以及受血清和c-Jun/AP-1调节的启动子活性。

Sequences of the 5'-flanking region of the human helix-loop-helix protein-encoding Id2A gene, and promoter activity regulated by serum and c-Jun/AP-1.

作者信息

Kurabayashi M, Jeyaseelan R, Kedes L

机构信息

Institute for Genetic Medicine, University of Southern California School of Medicine, Los Angeles 90033, USA.

出版信息

Gene. 1995 Apr 24;156(2):311-2. doi: 10.1016/0378-1119(95)00017-z.

DOI:10.1016/0378-1119(95)00017-z
PMID:7758976
Abstract

The 5'-flanking region of the human Id2A gene between nt -1213 and +36 from the putative transcription start point was sequenced. Transient transfection studies showed that the region between nt -834 and +30 directs the expression of a reporter gene and contains regulatory elements responsive to serum and c-Jun/AP-1 over production.

摘要

对人Id2A基因推定转录起始点上游-1213至+36核苷酸之间的5'侧翼区域进行了测序。瞬时转染研究表明，-834至+30核苷酸之间的区域指导报告基因的表达，并含有对血清和c-Jun/AP-1过量产生有反应的调控元件。

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