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[一种用于额肌悬吊上睑下垂手术的新型生物材料:大孔径聚四氟乙烯]

[A new biomaterial in surgery of ptosis with frontalis suspension: wide pore PTFE].

作者信息

Ruban J M, Mallem M, Tabone E, Donne C

机构信息

Clinique Ophtalmologique Universitaire A, Hôpital E.-Herriot, Lyon.

出版信息

J Fr Ophtalmol. 1995;18(3):207-19.

PMID:7759760
Abstract

BACKGROUND

In brow suspension, there is agreement that fresh tissue (autogenous fascia lata or temporalis fascia) provides the best results in terms of low complications and duration of the effect. Yet, the morbidity of fresh tissue harvesting is not negligible. Many alternative materials have disadvantages in terms of duration of the procedure and side effects.

METHODS

We have used a new material: wide porous expanded polytetrafluoroethylene (eP.T.F.E.). This material is an inert vitreous teflon alloplast with a high biocompatibility. It is close to Gore-Tex, but differs from it by a higher porosity (over 90%) and wider diameter of its pores (over 50 mus). We performed a series of 60 brow suspension from February 1992 to March 1994, using this new material.

RESULTS

We did not encounter any significant complications due to the material and in circumstance, we did not deplore any migration, infection or extrusion of the ePTFE. The biocompatibility seems to be increased, as it has been demonstrated by light and electron microscopy of the implanted material who revealed that fibrovascular ingrowth was significantly achieve two months after surgery.

CONCLUSION

The first results of this series are very encouraging. They can favourably be compared with the results of other series using different types of materials available in brow suspension. Though our longest follow-up is 30 months, further study is necessary to evaluate the long term results and eventual long term side effects of ePTFE, which avoid harvesting fresh tissues, thus reducing the brow suspension procedure's morbidity.

摘要

背景

在眉悬吊术中,人们一致认为新鲜组织(自体阔筋膜或颞肌筋膜)在低并发症和效果持续时间方面能提供最佳结果。然而,获取新鲜组织的发病率不可忽视。许多替代材料在手术持续时间和副作用方面存在缺点。

方法

我们使用了一种新材料:宽孔膨化聚四氟乙烯(ePTFE)。这种材料是一种具有高生物相容性的惰性玻璃态聚四氟乙烯异体移植物。它与戈尔薄膜相近,但孔隙率更高(超过90%)且孔径更大(超过50微米)。从1992年2月至1994年3月,我们使用这种新材料进行了一系列60例眉悬吊术。

结果

我们未遇到因该材料引起的任何严重并发症,在这种情况下,我们也未发现ePTFE有任何移位、感染或挤出情况。生物相容性似乎有所提高,植入材料的光学显微镜和电子显微镜检查表明,术后两个月纤维血管长入显著,这证明了这一点。

结论

该系列的初步结果非常令人鼓舞。它们可以与使用眉悬吊术中其他可用材料类型的其他系列结果进行有利比较。尽管我们最长的随访时间为30个月,但仍需要进一步研究来评估ePTFE的长期结果和最终的长期副作用,ePTFE避免了获取新鲜组织,从而降低了眉悬吊术的发病率。

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