Yokoyama K, Itoman M, Shindo M, Kai H
Department of Orthopedic Surgery, Kitasato University School of Medicine, Japan.
J Trauma. 1995 May;38(5):788-93. doi: 10.1097/00005373-199505000-00019.
Ninety-five patients with severe open tibial fractures (96 fractures) were treated with nonoperative treatment alone (NO group, n = 16), immediate internal fixation (I group, n = 22), delayed internal fixation (D group, n = 34), or external fixation (EF group, n = 24). The D group was divided into a delayed internal fixation group following nonoperative treatment (D1 group, n = 14), and a delayed internal fixation group following external fixation (D2 group, n = 20). Using the classification system of Gustilo, there were 43 type IIIA, 42 type IIIB, and 11 type IIIC open tibial fractures. There were 17 deep infections (type IIIA, n = 3; IIIB, n = 12; IIIC, n = 2). The difference in the deep infection rate (DIR) between the type IIIA and type IIIB fractures was statistically significant (7.0% vs. 28.0%, p < 0.05). The DIRs in groups NO, I, D1, D2, and EF were 12.5, 27.3, 7.1, 35, and 4%, respectively. There was a significant difference in DIR between the D2 group and the EF group. The DIR in the D (D1 + D2) group and group I showed no significant difference. There was no relationship between the DIR and either Injury Severity Score or skin closure time. The authors of this study, therefore, do not feel there is an advantage to immediate internal fixation over delayed procedures for Gustilo type III open fractures of the tibia. However, careful attention must be given to the application of delayed internal fixation, especially intramedullary nailing, after external fixation.
95例严重开放性胫骨骨折(96处骨折)患者分别接受单纯非手术治疗(非手术组,n = 16)、一期内固定(I组,n = 22)、延期内固定(D组,n = 34)或外固定(EF组,n = 24)。D组又分为非手术治疗后的延期内固定组(D1组,n = 14)和外固定后的延期内固定组(D2组,n = 20)。根据Gustilo分类系统,有43例IIIA型、42例IIIB型和11例IIIC型开放性胫骨骨折。发生深部感染17例(IIIA型,n = 3;IIIB型,n = 12;IIIC型,n = 2)。IIIA型和IIIB型骨折的深部感染率(DIR)差异有统计学意义(7.0%对28.0%,p < 0.05)。非手术组、I组、D1组、D2组和EF组的DIR分别为12.5%、27.3%、7.1%、35%和4%。D2组和EF组的DIR有显著差异。D(D1 + D2)组和I组的DIR无显著差异。DIR与损伤严重程度评分或皮肤闭合时间均无相关性。因此,本研究的作者认为,对于Gustilo III型开放性胫骨骨折,一期内固定并不比延期手术有优势。然而,必须谨慎应用延期内固定,尤其是外固定后的髓内钉固定。