Zamotaev I P, Sokolova V I, Konstantinova L A, Pozdniakova V P
Antibiotiki. 1976 Mar;21(3):266-9.
Efficiency of sodium dicloxacillin in the form of capsules prepared at the All-Union Research Institute of Antibiotics was studied in treatment of 23 patients with acute pneumonia (mainly of staphylococcal etiology) and 16 patients with chronic pneumonia at the stage of exacerbation. High therapeutic effect of dicloxacillin in treatment of acute pneumonia in a daily dose of 4--5 gm was found. Satisfactory results were obtained with combined use of dicloxacillin and benzylpenicillin. In treatment of chronic pneumonia dicloxacillin was less effective. No toxic effect of dicloxacillin on the parenchymatose organs and peripheral blood was registered.
全苏抗生素研究所制备的双氯西林钠胶囊治疗23例急性肺炎(主要为葡萄球菌病因)和16例慢性肺炎急性加重期患者的疗效进行了研究。发现双氯西林钠每日剂量4 - 5克治疗急性肺炎有很高的疗效。双氯西林钠与苄青霉素联合使用取得了满意的结果。在治疗慢性肺炎时双氯西林钠效果较差。未发现双氯西林钠对实质器官和外周血有中毒作用。