Lachowicz T M, Swiderski M
Arch Immunol Ther Exp (Warsz). 1976;24(2):185-90.
Changes in composition of Escherichia coli were followed during antibiotic therapy of nin children with acute diarrhea. In five cases enteropathogenic serotypes of E. coli were multiple-drug resistant, and in four other this feature characterized nonpathogenic E. coli strains. The results point to the importance of choice of the drugs effective not only against pathogenic serotypes, but also against nonpathogenic ones, and uselessness and even harmfulness of chemotherapy "in blindly".
在对9名急性腹泻儿童进行抗生素治疗期间，对大肠杆菌的组成变化进行了跟踪研究。5例中致病性大肠杆菌血清型具有多重耐药性，另外4例中该特征表现在非致病性大肠杆菌菌株上。结果表明，选择不仅对致病性血清型有效，而且对非致病性血清型也有效的药物很重要，盲目进行化疗是无用的甚至是有害的。
