Puchmayer V
IV. interní klinika, 1. LF UK, Praha.
Vnitr Lek. 1995 Mar;41(3):204-6.
The author reviews contemporary knowledge of the pathogenesis of ischaemia of the lower extremities. As to therapeutic provision which influence in a favourable way pathological processes associated with the development of ischaemia an important place is held by pentoxiphylline (Trental) which reduces the pathologically raised adhesiveness and activity of leucocytes causing an excessive immune response; it reduces the viscosity of blood and procoagulation activity.
作者回顾了当下关于下肢缺血发病机制的知识。至于对与缺血发展相关的病理过程产生有利影响的治疗措施，己酮可可碱（曲克芦丁）占有重要地位，它能降低因过度免疫反应而导致的白细胞病理性升高的黏附性和活性；还能降低血液黏度和促凝血活性。
