Würtz F G, Dinges H P, Radner H, Kleinert R
Institute of Pathology, Landeskrankenhaus, Klagenfurt, Austria.
Acta Cytol. 1995 May-Jun;39(3):577-85.
In a 42-year-old women a recurrent anaplastic ependymoma of the frontal lobe developed intracerebral metastases and, after implantation of an atrioventricular shunt, also metastasized to the lung, pleural cavity and mediastinal lymph nodes. In routinely stained smear preparations of the pleural effusion sediment, the typical cytologic features of an anaplastic ependymoma were found--papilliform cell clusters with acellular axes ("pseudorosettes"), incomplete true ependymal rosettes, and epithelioid and tanycytoid tumor cells with signs of anaplasia. A peculiar matrix material was a characteristic feature of this case and, to our knowledge, was not reported previously. It consisted of refringent, fibrillar strands composed of tightly packed, roundish to rodshaped granules. This matrix seemed to be associated with the cytoplasmic processes of the tumor cells.
一名42岁女性患有复发性额叶间变性室管膜瘤，发生了脑内转移，在植入房室分流器后，还转移至肺、胸腔和纵隔淋巴结。在胸腔积液沉淀物的常规染色涂片标本中，发现了间变性室管膜瘤的典型细胞学特征——具有无细胞轴心的乳头状细胞簇（“假菊形团”）、不完全的真性室管膜菊形团，以及具有间变迹象的上皮样和伸长细胞样肿瘤细胞。一种特殊的基质物质是该病例的特征性表现，据我们所知，此前未见报道。它由折光性强的纤维状条索组成，这些条索由紧密排列的圆形至杆状颗粒构成。这种基质似乎与肿瘤细胞的胞质突起有关。
