Lewis R J, Bingham J P, Jones A, Alewood P F, Andrews P R
Drug Design and Development (3D) Centre, Gehrmann Laboratories, University of Queensland, St Lucia.
Australas Biotechnol. 1994 Sep-Oct;4(5):298-300.
Australian cone shell venoms are being investigated as an exciting new source of bioactive peptides as part of a new collaborative project between the 3D Centre and AMRAD. Initial studies have already revealed a number of new and novel acting peptides amongst the hundred or so small, heavily constrained peptides present in the venom of each cone shell. The aim of the project is to develop peptidomimetic drugs based on a selection of these native peptides.
作为3D中心与AMRAD之间一个新的合作项目的一部分，澳大利亚芋螺毒液正作为生物活性肽的一个令人兴奋的新来源进行研究。初步研究已经在每种芋螺毒液中存在的约一百种小的、结构高度受限的肽中发现了许多新的和具有新作用方式的肽。该项目的目的是基于这些天然肽中的一部分开发拟肽药物。
