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一种编码与哺乳动物醛脱氢酶非常相似的蛋白质的集胞藻属基因的克隆与测序。

Cloning and sequencing of a Synechococcus gene encoding a protein very similar to mammalian aldehyde dehydrogenases.

作者信息

Kashiwagi S, Irie J, Kanamaru K, Mizuno T

机构信息

Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Japan.

出版信息

Biosci Biotechnol Biochem. 1994 Dec;58(12):2299-300. doi: 10.1271/bbb.58.2299.

DOI:10.1271/bbb.58.2299
PMID:7765727
Abstract

We report cloning and sequencing of a gene encoding a putative aldehyde dehydrogenase in Synechococcus sp. PCC7942. It was found that this phototrophic microorganism has a protein very similar to mammalian class-3 aldehyde dehydrogenases. A mutant strain lacking this gene was hypersensitive in growth to an aromatic aldehyde.

摘要

我们报道了聚球藻属PCC7942中一个编码假定醛脱氢酶的基因的克隆和测序。发现这种光合微生物有一种与哺乳动物3类醛脱氢酶非常相似的蛋白质。一个缺失该基因的突变株在生长过程中对芳香醛高度敏感。

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