Levy J G
Quadra Logic Technologies Inc., Vancouver, BC, Canada.
Trends Biotechnol. 1995 Jan;13(1):14-8. doi: 10.1016/S0167-7799(00)88895-2.
Photodynamic therapy (PDT) involves the use of a class of molecules that are activated by light, and which accumulate in, and are retained by, certain abnormal tissues. When these molecules (known as photosensitizers) are activated by light, they cause the formation of active forms of oxygen, which result in the killing of cells in which the photosensitizers are present. Thus, PDT can be used to destroy diseased areas of tissue selectively, while sparing the normal surrounding tissue. PDT has been extensively studied in the treatment of cancer, but the technology has potential as a treatment in a number of other disease conditions.
光动力疗法(PDT)涉及使用一类可被光激活的分子,这些分子会在某些异常组织中积聚并留存。当这些分子(称为光敏剂)被光激活时,它们会促使活性氧的形成,从而导致存在光敏剂的细胞死亡。因此,光动力疗法可用于选择性地破坏病变组织区域,同时保留周围的正常组织。光动力疗法在癌症治疗方面已得到广泛研究,但该技术在治疗许多其他疾病方面也具有潜力。