Demling R H, Ellerbe S, Lowe N J
Arch Surg. 1978 Jun;113(6):758-9. doi: 10.1001/archsurg.1978.01370180100019.
Toxic epidermal necrolysis is the name given to a group of dermatologic disorders characterized by a separation of epidermis and dermis with a subsequent skin slough. The denuded areas have the appearance of a second-degree burn. The complications of infection, negative nitrogen balance, severe pain, and emotional instability are identical to those seen in the patient with major burns. There are difficulties in patient management and advantages in burn unit care. As with the major burn, care of the patient with skin loss from toxic epidermal necrolysis is extremely complex, requiring the expertise of a burn team along with that of the dermatologist.
中毒性表皮坏死松解症是一组皮肤疾病的名称，其特征为表皮与真皮分离，随后皮肤脱落。裸露区域呈现二度烧伤的外观。感染、负氮平衡、剧痛和情绪不稳定等并发症与严重烧伤患者所见的并发症相同。患者管理存在困难，而烧伤病房护理则具有优势。与严重烧伤一样，中毒性表皮坏死松解症导致皮肤缺失患者的护理极其复杂，需要烧伤团队以及皮肤科医生的专业知识。
