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嚼食巧茶会延迟半固体食物的胃排空。

Khat chewing delays gastric emptying of a semi-solid meal.

作者信息

Heymann T D, Bhupulan A, Zureikat N E, Bomanji J, Drinkwater C, Giles P, Murray-Lyon I M

机构信息

Department of Gastroenterology, Charing Cross Hospital, London, UK.

出版信息

Aliment Pharmacol Ther. 1995 Feb;9(1):81-3. doi: 10.1111/j.1365-2036.1995.tb00356.x.

Abstract

BACKGROUND

The leaves of Khat are chewed for their central stimulant effect, but their use may cause anorexia and constipation.

METHODS

Gastric emptying of a radio-labelled semi-solid meal was measured in 12 healthy volunteers on two occasions a week apart. Subjects chewed either Khat leaves (Catha edulis) or lettuce for 2 h before the study.

RESULTS

Gastric emptying was significantly (P < 0.02) prolonged after chewing Khat compared with lettuce.

CONCLUSION

The sympathomimetic action of cathinone in Khat may cause the observed delay in gastric emptying.

摘要

背景

巧茶树叶因其具有中枢兴奋作用而被咀嚼,但使用后可能会导致厌食和便秘。

方法

在12名健康志愿者中,每周两次测量放射性标记半固体餐的胃排空情况,两次测量间隔一周。在研究前,受试者咀嚼巧茶树叶(Catha edulis)或生菜2小时。

结果

与咀嚼生菜相比,咀嚼巧茶树叶后胃排空显著延长(P < 0.02)。

结论

巧茶中卡西酮的拟交感神经作用可能导致观察到的胃排空延迟。

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