Murakami T, Nakamura H, Tsuda K, Ishida T, Tomoda K, Hori S, Monden M, Kanai T, Wakasa K, Sakurai M
Department of Radiology, Osaka University Medical School, Japan.
J Magn Reson Imaging. 1995 Mar-Apr;5(2):165-70. doi: 10.1002/jmri.1880050210.
The authors describe the enhanced magnetic resonance (MR) imaging appearance of intrahepatic cholangiocarcinoma. The MR images of eight patients with intrahepatic cholangiocarcinoma who underwent MR examination within 3 weeks before partial hepatectomy were retrospectively studied. The MR images, including a dynamic study, were compared directly with pathologic and histologic findings. The peripheral region of the medullary subtype of cholangiocarcinoma, with many tumor cells, showed greater enhancement relative to liver parenchyma in the early phase. The peripheral region of the scirrhous subtype, with fewer tumor cells showed less enhancement in the early phase. In one patient, the thin rim of the medullary tumor showed less enhancement in the late phase, and this rim corresponded to the peripheral region of the medullary tumor with many tumor cells. The central region of tumors with a large amount of fibrous tissue showed prolonged enhancement in the late and delayed phases. The thin rim of liver parenchyma around the tumor showed less enhancement in the early phase and greater enhancement in the late phase; this rim corresponded to congestive liver parenchyma with dilated sinusoids. Intrahepatic cholangiocarcinoma shows various enhancement patterns, which depend on both the histologic subtype and the degree and distribution of fibrosis within the tumor.
作者描述了肝内胆管癌的增强磁共振（MR）成像表现。回顾性研究了8例在肝部分切除术前3周内接受MR检查的肝内胆管癌患者的MR图像。将包括动态研究在内的MR图像与病理和组织学结果直接进行比较。胆管癌髓样亚型的外周区域有许多肿瘤细胞，在早期相对于肝实质显示出更强的强化。硬化型亚型的外周区域肿瘤细胞较少，在早期强化较少。在1例患者中，髓样肿瘤的薄边缘在晚期强化较少，该边缘对应于有许多肿瘤细胞的髓样肿瘤外周区域。有大量纤维组织的肿瘤中央区域在晚期和延迟期显示出延迟强化。肿瘤周围肝实质的薄边缘在早期强化较少，在晚期强化较多；该边缘对应于窦状隙扩张的充血性肝实质。肝内胆管癌表现出多种强化模式，这取决于组织学亚型以及肿瘤内纤维化的程度和分布。
