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脉冲Nd:YAG激光与CO2激光对主动脉瓣作用的比较研究

A comparative study of pulsed Nd:YAG and CO2 laser effect on aortic valves.

作者信息

Yova D, Kassis K, Agapitos E, Kavantzas N, Koutsouris D, Serafetinides A

机构信息

National Technical University of Athens, Department of Electrical and Computer Engineering, Greece.

出版信息

Technol Health Care. 1995 Mar;3(1):53-9.

PMID:7767689
Abstract

Laser angioplasty is a promising new technology, which sometimes offers the surgeon an alternative tool to conventional therapy. One of the main prerequisites of using powerful pulsed lasers in angioplasty is the optimum choice of the irradiation parameters (the wavelength, the pulse shape and duration, the energy parameters). Infrared lasers have numerous applications in surgery. Among them the pulsed CO2 laser emitting at 10.6 microns and the pulsed Nd:YAG laser emitting at 1.064 microns are the most widely used, since the delivery of laser energy in short pulses of high peak pulse power limits distant thermal effects. The CO2 laser wavelength is greatly absorbed by tissue water, while the Nd:YAG laser wavelength is poorly absorbed by water or other tissue chromophores, affecting deeper the tissue. The CO2 laser incises effectively the tissue, but presents inadequate coagulation, while the Nd:YAG laser seems to present better coagulation properties. In this work, a comparative study of pulsed Nd:YAG and CO2 lasers in ablating cardiovascular tissue, is presented. The irradiation regime of the two lasers is determined, for the specific tissue and/or pathology. Also the depth of thermally induced coagulation is measured. The results are presented according to the efficacy of each laser for incision and/or coagulation.

摘要

激光血管成形术是一项很有前景的新技术,有时能为外科医生提供一种替代传统疗法的工具。在血管成形术中使用高功率脉冲激光的主要前提条件之一是最佳选择照射参数(波长、脉冲形状和持续时间、能量参数)。红外激光在外科手术中有众多应用。其中,发射波长为10.6微米的脉冲二氧化碳激光和发射波长为1.064微米的脉冲钕钇铝石榴石激光应用最为广泛,因为以高峰值脉冲功率的短脉冲形式传输激光能量可限制远距离热效应。二氧化碳激光的波长能被组织中的水大量吸收,而钕钇铝石榴石激光的波长则不易被水或其他组织发色团吸收,对组织的穿透更深。二氧化碳激光能有效切割组织,但凝血效果欠佳,而钕钇铝石榴石激光似乎具有更好的凝血特性。在这项工作中,展示了对脉冲钕钇铝石榴石激光和二氧化碳激光在消融心血管组织方面的对比研究。针对特定的组织和/或病理情况,确定了两种激光的照射方式。同时测量了热诱导凝血的深度。根据每种激光在切割和/或凝血方面的效果呈现结果。

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