Klein M K, Powers B E, Withrow S J, Curtis C R, Straw R C, Ogilvie G K, Dickinson K L, Cooper M F, Baier M
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523, USA.
J Am Vet Med Assoc. 1995 Apr 1;206(7):1007-9.
Of 82 dogs with thyroid carcinoma seen between January 1981 and October 1989, 20 had freely movable tumors without evidence of metastasis and were treated with surgical excision alone. Uncensored mean and median survival times for these 20 dogs were both 20.5 months. Kaplan-Meier survival analysis, which censors for nontumor-related deaths and dogs lost to follow-up, indicated that median survival time was greater than 36 months. Seven dogs died of tumor-related causes: 2 died because of metastasis or local recurrence of the tumor, 5 died of treatment-related complications (eg, laryngeal paralysis, hypocalcemia, tracheostomy complications). Eight dogs died of unrelated causes; 1 dog was lost to follow-up at 26 months after surgery; 3 dogs were alive 19, 24, and 26 months after surgery. Cause of death could not be determined in the remaining dog. Long-term survival is possible following surgical removal of mobile thyroid carcinomas in dogs.
在1981年1月至1989年10月期间所见的82只患有甲状腺癌的犬中，20只犬的肿瘤可自由移动且无转移迹象，仅接受了手术切除治疗。这20只犬未经审查的平均生存时间和中位生存时间均为20.5个月。Kaplan-Meier生存分析对与肿瘤无关的死亡和失访犬进行了审查，结果表明中位生存时间超过36个月。7只犬死于与肿瘤相关的原因：2只因肿瘤转移或局部复发死亡，5只因治疗相关并发症（如喉麻痹、低钙血症、气管切开术并发症）死亡。8只犬死于无关原因；1只犬在术后26个月失访；3只犬在术后19、24和26个月时仍存活。其余1只犬的死亡原因无法确定。犬的可移动性甲状腺癌手术切除后有可能实现长期存活。
