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Pulmonary intravascular macrophages in the pathogenesis of bovine pulmonary lesions caused by Actinomyces pyogenes.

作者信息

Leifsson P S, Basse A, Jensen H E, Bloch B, Aalbaek B

机构信息

Department of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University Copenhagen, Frederiksberg C, Denmark.

出版信息

J Comp Pathol. 1995 Feb;112(2):197-206. doi: 10.1016/s0021-9975(05)80061-1.

DOI:10.1016/s0021-9975(05)80061-1
PMID:7769148
Abstract

Rabbit antisera raised against somatic antigens from two strains of Actinomyces pyogenes reacted specifically in a peroxidase anti-peroxidase technique which was developed for the location of the bacteria in formalin-fixed tissues. The technique was applied on experimental murine and spontaneous bovine lesions caused by A. pyogenes. By electron microscopy and immunohistochemistry it was demonstrated that pulmonary intravascular macrophages play a role in the uptake of A. pyogenes from the blood, and in the production of pyaemic pulmonary lesions.

摘要

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