Schlegel L, Chaumeil C, Quesnot S, Pean Y, Scat Y
Laboratoire de Biologie, Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris.
J Fr Ophtalmol. 1995;18(4):250-8.
This study evaluates the variability of the bacterial flora and the changes in their antibiotics sensitivity tests between 1988 and 1993 in 46090 specimens (conjunctival cultures, corneal scrapings, vitreous, aqueous humour, ocular foreign bodies).
The specimens were cultured and antibiotics sensitivity test was carried out on the pathogens only (3309 strains).
Streptococci (36.1%) and Staphylococcus aureus (35.6%) are the most frequent species with Enterobacteriaceae (12.1%) and Haemophilus (7.8%). S. aureus and Streptococcus pneumoniae are more prevalent with decreasing values for other bacteria (Khi-2 of trend, Mantel's extension, p < 0.05). Antibiotics sensitivity yield expected results without any remarkable changes during the study. No multi-resistant strain was isolated.
The increase of number of S. aureus and S. pneumoniae is the major change noted in pathogens found from our eye samples.
本研究评估了1988年至1993年间46090份标本（结膜培养物、角膜刮片、玻璃体、房水、眼内异物）中细菌菌群的变异性及其抗生素敏感性试验的变化。
对标本进行培养，并仅对病原体（3309株）进行抗生素敏感性试验。
链球菌（36.1%）和金黄色葡萄球菌（35.6%）是最常见的菌种，其次是肠杆菌科（12.1%）和嗜血杆菌（7.8%）。金黄色葡萄球菌和肺炎链球菌更为普遍，其他细菌的比例下降（趋势卡方检验、曼特尔扩展检验，p<0.05）。抗生素敏感性试验得出了预期结果，在研究期间没有任何显著变化。未分离出多重耐药菌株。
金黄色葡萄球菌和肺炎链球菌数量的增加是我们从眼部样本中发现的病原体的主要变化。
