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糖尿病患者的头颈部感染

Infections of the head and neck in diabetes mellitus.

作者信息

Tierney M R, Baker A S

机构信息

Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Infect Dis Clin North Am. 1995 Mar;9(1):195-216.

PMID:7769218
Abstract

Patients with diabetes mellitus exhibit particular susceptibility to three severe infections of the head and neck: rhinocerebral mucormycosis, postoperative endophthalmitis, and malignant otitis externa. Rhinocerebral mucormycosis is an extensive life-threatening infection beginning in the nasal passages and sinuses and extending often into the orbit and the cerebrum. Endophthalmitis, which is infection of the vitreal contents, can occur secondary to bacteremia, trauma, or postoperatively. Invasive external otitis or malignant otitis externa is an invasive infection beginning in the adjacent soft tissue and into bone. It is usually secondary to Pseudomonas aeruginosa and occurs almost exclusively in diabetics. These will all be discussed in this article.

摘要

糖尿病患者对三种严重的头颈部感染表现出特殊易感性

鼻脑毛霉菌病、术后眼内炎和恶性外耳道炎。鼻脑毛霉菌病是一种广泛的、危及生命的感染,始于鼻腔和鼻窦,常蔓延至眼眶和大脑。眼内炎是玻璃体内容物的感染,可继发于菌血症、外伤或术后。侵袭性外耳道炎或恶性外耳道炎是一种始于相邻软组织并侵入骨质的侵袭性感染。它通常继发于铜绿假单胞菌,几乎仅发生于糖尿病患者。本文将对这些疾病进行讨论。

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1
Infections of the head and neck in diabetes mellitus.糖尿病患者的头颈部感染
Infect Dis Clin North Am. 1995 Mar;9(1):195-216.
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Case report: rhinocerebral mucormycosis in association with diabetes mellitus.
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Successful treatment of rhino-cerebral mucormycosis with dual antifungal therapy and minimal surgical debridement.采用双重抗真菌治疗和最小限度手术清创成功治疗鼻脑型毛霉菌病。
IDCases. 2022 Sep 6;30:e01615. doi: 10.1016/j.idcr.2022.e01615. eCollection 2022.
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Mucormycosis Following Tooth Extraction in a Diabetic Patient: A Case Report.糖尿病患者拔牙后发生毛霉菌病:一例报告
Cureus. 2020 Aug 15;12(8):e9757. doi: 10.7759/cureus.9757.
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Rhinocerebral Mucormycosis Among Diabetic Patients: An Emerging Trend.糖尿病患者的鼻脑毛霉菌病:一种新兴趋势。
Mycopathologia. 2015 Dec;180(5-6):389-96. doi: 10.1007/s11046-015-9934-x. Epub 2015 Sep 9.
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A Fatal Outcome of Rhino-orbito-cerebral Mucormycosis Following Tooth Extraction: A Case Report.拔牙后鼻眶脑型毛霉病的致命结局:一例报告
J Int Oral Health. 2015;7(Suppl 1):68-71.
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Cystic fibrosis presenting with corneal perforation and crystalline lens extrusion.表现为角膜穿孔和晶状体脱出的囊性纤维化
J R Soc Med. 2010 Jul;103 Suppl 1(Suppl 1):S30-3. doi: 10.1258/jrsm.2010.s11008.
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[Topical immunomodulation. A milestone for the treatment of therapy-resistant noninfectious chronic external otitis?].
HNO. 2008 May;56(5):530-4, 536-7. doi: 10.1007/s00106-007-1615-8.
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First isolation of Burkholderia cepacia from a deep neck abscess in a diabetic patient successfully treated with hyperbaric oxygen.首次从一名接受高压氧成功治疗的糖尿病患者的深部颈部脓肿中分离出洋葱伯克霍尔德菌。
J Clin Microbiol. 2005 Jan;43(1):529. doi: 10.1128/JCM.43.1.529.2005.
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Macrophage function in alloxan diabetic mice: expression of adhesion molecules, generation of monokines and oxygen and NO radicals.四氧嘧啶糖尿病小鼠中的巨噬细胞功能:黏附分子的表达、单核因子的产生以及氧和一氧化氮自由基
Clin Exp Immunol. 1998 Oct;114(1):13-8. doi: 10.1046/j.1365-2249.1998.00687.x.