Dalekos G N, Zervou E, Karabini F, Elisaf M, Bourantas K, Siamopoulos K C
Department of Internal Medicine, University Hospital of Ioannina, Greece.
Transfusion. 1995 Jun;35(6):503-6. doi: 10.1046/j.1537-2995.1995.35695288770.x.
In addition to human immunodeficiency virus, human T-lymphotropic virus types I and II (HTLV-I/II) is prevalent among blood donors in the United States. In Greece, there are no epidemiologic data regarding the prevalence of HTLV-I/II among volunteer blood donors and high-risk groups.
To determine the prevalence of HTLV-I/II infections in northwestern Greece, a seroepidemiologic study was conducted among volunteer blood donors, multiply transfused patients, heroin addicts, and chronic hemodialysis patients. The subjects were tested for serologic evidence of HTLV-I/II infection by enzyme immunoassays and specific protein immunoblot confirmatory test.
None of the volunteer blood donors and heroin addicts had detectable antibodies to HTLV-I/II. Only 1 (1.45%) of the 69 multiply transfused patients had indeterminate results, while 2 (1.2%) of 163 hemodialysis patients were positive.
In northwestern Greece, routine screening for HTLV-I and HTLV-II infections does not appear to be required. However, the finding of seropositivity among hemodialysis patients requires further evaluation of the origin of the infection, as its zero prevalence in this population seems to exclude transfusion transmission.
除了人类免疫缺陷病毒外，I型和II型人类嗜T淋巴细胞病毒（HTLV-I/II）在美国献血者中也很普遍。在希腊，没有关于志愿献血者和高危人群中HTLV-I/II流行率的流行病学数据。
为了确定希腊西北部HTLV-I/II感染的流行率，对志愿献血者、多次输血患者、海洛因成瘾者和慢性血液透析患者进行了血清流行病学研究。通过酶免疫测定和特异性蛋白免疫印迹确认试验检测受试者是否有HTLV-I/II感染的血清学证据。
志愿献血者和海洛因成瘾者均未检测到HTLV-I/II抗体。69例多次输血患者中只有1例（1.45%）结果不确定，而163例血液透析患者中有2例（1.2%）呈阳性。
在希腊西北部，似乎不需要对HTLV-I和HTLV-II感染进行常规筛查。然而，血液透析患者中血清阳性的发现需要对感染源进行进一步评估，因为该人群中零流行率似乎排除了输血传播。
