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Assembly of the postsynaptic apparatus.

作者信息

Apel E D, Merlie J P

机构信息

Department of Molecular Biology and Pharmacology, Washington Universty School of Medicine, St Louis, Missouri 63110, USA.

出版信息

Curr Opin Neurobiol. 1995 Feb;5(1):62-7. doi: 10.1016/0959-4388(95)80088-3.

DOI:10.1016/0959-4388(95)80088-3
PMID:7773008
Abstract

Recent research has led to a clearer picture of the molecular organization of the postsynaptic apparatus at the developing neuromuscular junction. In addition, one link between the extracellular signaling molecule agrin and the intracellular events that mediate formation of acetylcholine receptor clusters has been established with the identification of an argin-binding protein.

摘要

相似文献

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Assembly of the postsynaptic apparatus.
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2
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alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering.α-辅肌动蛋白与聚集素刺激的 AChR 簇集过程中的rapsyn 相互作用。
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Src-family kinases stabilize the neuromuscular synapse in vivo via protein interactions, phosphorylation, and cytoskeletal linkage of acetylcholine receptors.
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The dystroglycan complex is necessary for stabilization of acetylcholine receptor clusters at neuromuscular junctions and formation of the synaptic basement membrane.肌营养不良蛋白聚糖复合体对于神经肌肉接头处乙酰胆碱受体簇的稳定以及突触基底膜的形成是必需的。
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Roles of rapsyn and agrin in interaction of postsynaptic proteins with acetylcholine receptors.rapsyn和聚集蛋白在突触后蛋白与乙酰胆碱受体相互作用中的作用。
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10
Agrin can mediate acetylcholine receptor gene expression in muscle by aggregation of muscle-derived neuregulins.聚集蛋白可通过肌肉衍生的神经调节蛋白的聚集来介导肌肉中乙酰胆碱受体基因的表达。
J Cell Biol. 1998 May 4;141(3):715-26. doi: 10.1083/jcb.141.3.715.