Schmid H A, Raykhtsaum G
Pineal Research Laboratory, VA Medical Center, Providence, RI 02908, USA.
J Pineal Res. 1995 Jan;18(1):12-20. doi: 10.1111/j.1600-079x.1995.tb00134.x.
Pineal tissue calcifications (male, ages 14, 47, 62, 82), which were metallographically embedded and polished at controlled levels and studied by transmission electron microscopy and microanalytic spectroscopy, showed age-related differences. Results show that concentrically arranged crescent-shaped lamellae increase in number and decrease in width with age. Calcium (Ca) and phosphorus (P) per point measurements in dark and light lamellae at various distances from the core show Ca/P molar ratios between 1.49-1.62 in the 82-year-old specimen as compared to 1.26 to 1.41 in the younger specimens. The 62-year-old specimens show a decrease in P and an increase in Ca from periphery to center. These data and other descriptive details suggest that the sum of these changes represent remodelling of the mineralogical structure within the same calcification throughout the life span.
松果体组织钙化（男性，年龄分别为14岁、47岁、62岁、82岁），经过金相嵌入并在可控水平下抛光，然后通过透射电子显微镜和微分析光谱进行研究，结果显示出与年龄相关的差异。结果表明，同心排列的新月形薄片数量随年龄增加而增多，宽度随年龄增加而减小。在距核心不同距离处对暗层和亮层进行的钙（Ca）和磷（P）逐点测量显示，82岁标本中暗层和亮层的Ca/P摩尔比在1.49 - 1.62之间，而较年轻标本中的该比值在1.26至1.41之间。62岁标本从周边到中心显示出P含量减少而Ca含量增加。这些数据和其他描述性细节表明，这些变化的总和代表了同一钙化在整个生命周期内矿物结构的重塑。
