Sugihara H, Tamaki N, Nozawa M, Inamoto Y, Taniguchi Y, Aoki E, Mitsunami K, Kinoshita M
Department of Internal Medicine, Takashima General Hospital.
Kaku Igaku. 1995 Apr;32(4):359-65.
To improve the quality of 24 hours delayed images (24 DL) of stress thallium-201 myocardial SPECT, reinjection was performed at 24 hours later (24 RI), and the results were compared with those of 24 DL. A total of 45 patients were studied, including 18 patients in 24 DL, 27 patients in 24 RI. All of them showed persistent defect or incomplete redistribution on the routine stress and 3 hours delayed SPECT scans. In 24 RI, 37 MBq of thallium-201 was reinjected at 24 hours later. Myocardial count of 24 DL was about 1/4 of stress image, while 24 RI was about 1/2. Quality of 24 RI image was nearly equal to 3 hours delayed image. Of regions without redistribution at 3 hours delayed image, 5 (36%) regions showed new redistribution at 24 RI. Of regions incomplete redistribution, 6 (25%) regions showed further redistribution. Compared with 24 DL, the frequency of redistribution tended to be higher in this protocol than that of the 24 DL (11%, 17% respectively). In conclusion, the reinjection at 24 hours delayed imaging was considered to be useful to evaluate viability of myocardium in patient with CAD.
为提高心肌灌注铊-201单光子发射计算机断层扫描(SPECT)的24小时延迟影像(24 DL)质量,在24小时后进行再注射(24 RI),并将结果与24 DL进行比较。共研究了45例患者,其中24 DL组18例,24 RI组27例。所有患者在常规负荷及3小时延迟SPECT扫描中均显示持续性缺损或不完全再分布。在24 RI组中,24小时后再注射37 MBq铊-201。24 DL的心肌计数约为负荷影像的1/4,而24 RI约为1/2。24 RI影像质量与3小时延迟影像几乎相等。在3小时延迟影像无再分布的区域中,5个(36%)区域在24 RI时出现新的再分布。在不完全再分布区域中,6个(25%)区域出现进一步再分布。与24 DL相比,该方案中再分布频率倾向于高于24 DL(分别为11%、17%)。总之,24小时延迟显像时的再注射被认为有助于评估冠心病患者心肌的存活情况。