Donnenfeld E D, Selkin B A, Perry H D, Moadel K, Selkin G T, Cohen A J, Sperber L T
Lions Eye Bank for Long Island, North Shore University Hospital, Manhasset, NY 11030, USA.
Ophthalmology. 1995 Jun;102(6):979-84. doi: 10.1016/s0161-6420(95)30926-8.
Treating traumatic corneal abrasions is a common problem for the ophthalmologist. Traditional management has been the use of a pressure patch. Three different therapeutic modalities were evaluated for their efficacy in treating traumatic corneal abrasions.
Forty-seven consecutive patients with traumatic corneal abrasions were randomized prospectively in a single-masked, controlled clinical trial which compared the efficacy of (1) pressure patching, (2) a bandage contact lens, and (3) a bandage contact lens with a topical nonsteroidal anti-inflammatory drug (0.5% ketorolac tromethamine).
There was no significant difference in the healing time of the three groups. However, psychometric analysis showed a significant decrease in pain in the group that received a bandage contact lens with a topical nonsteroidal anti-inflammatory drug. There was a significant difference in the ability to return to normal activities in both contact lens groups compared with the pressure-patch group. There was no significant difference among the three groups with respect to photophobia, redness, ocular irritation, headache, or tearing.
Use of a bandage contact lens significantly shortens the time required for a patient to return to normal activities. Moreover, addition of a nonsteroidal anti-inflammatory drug to a treatment regimen significantly decreases the pain associated with traumatic corneal abrasions. Use of a bandage contact lens with a topical nonsteroidal anti-inflammatory may prove to be an effective adjunct in treating traumatic corneal abrasions.
治疗外伤性角膜擦伤是眼科医生常见的问题。传统的治疗方法是使用加压眼罩。评估了三种不同治疗方式治疗外伤性角膜擦伤的疗效。
47例连续的外伤性角膜擦伤患者被前瞻性地随机纳入一项单盲对照临床试验,比较(1)加压眼罩、(2)绷带式隐形眼镜和(3)含局部非甾体抗炎药(0.5%酮咯酸氨丁三醇)的绷带式隐形眼镜的疗效。
三组的愈合时间无显著差异。然而,心理测量分析显示,接受含局部非甾体抗炎药的绷带式隐形眼镜治疗的组疼痛显著减轻。与加压眼罩组相比,两个隐形眼镜组恢复正常活动的能力有显著差异。三组在畏光、眼红、眼部刺激、头痛或流泪方面无显著差异。
使用绷带式隐形眼镜可显著缩短患者恢复正常活动所需的时间。此外,在治疗方案中添加非甾体抗炎药可显著减轻与外伤性角膜擦伤相关的疼痛。使用含局部非甾体抗炎药的绷带式隐形眼镜可能是治疗外伤性角膜擦伤的一种有效辅助方法。