Mitinskaia L A, Elufimova V F, Iukhimenko N V, Demeshko N D, Zriachkina L I, Pesnia N P
Probl Tuberk. 1995(2):5-6.
70 children aged 4-15 with growing tuberculin sensitivity received preventive treatment with isoniazid in children's sanatorium. The drug was taken for 2 or 3 months in a dose 10 mg/kg daily (19 and 51 children, respectively). Preventive isoniazid course proved effective as none of the children treated developed tuberculosis within 3 years. The 3-month course is preferable as it is more potent in relation to tuberculin sensitivity immediately after the treatment termination and 1, 2 years after it.
70名4至15岁结核菌素敏感性增强的儿童在儿童疗养院接受了异烟肼预防性治疗。分别有19名和51名儿童，每日服用剂量为10mg/kg的该药物2个月或3个月。预防性异烟肼疗程被证明是有效的，因为在接受治疗的儿童中，3年内无人患结核病。3个月疗程更可取，因为在治疗结束后即刻以及治疗后1年和2年时，它对结核菌素敏感性的作用更强。
