犬白细胞抗原A、B和D抗原匹配与无关比格犬皮肤同种异体移植存活情况

Matching for DLA-A, DLA-B and DLA-D antigens and skin allograft survival in unrelated beagle dogs.

作者信息

Abb J, Grosse-Wilde H, Scholz S, Albert E D

出版信息

Eur Surg Res. 1978;10(2):142-5. doi: 10.1159/000128002.

Abstract

The effect of matching for immunogenetic markers on the survival of skin allografts in unrelated dogs has been studied. Skin grafts in recipients differing from donors for either DLA-A or DLA-B antigens, or both, had mean survival times (MST) of 9.3, 9.7 and 8.5 days, respectively. Differences between these groups were not significant. Prolonged survival of skin grafts, however, was found in SK-LD-indentical (MST: 12.4 days) or SD-identical/LD-different (MST: 12.5 days) donor-recipient combinations. We conclude that dkin allograft survival in dogs appears to be controlled by DLA-A and DLA-B, but not by DLA-D determinants.

摘要

对不相关犬类进行免疫遗传标记匹配对皮肤同种异体移植存活的影响已得到研究。在DLA - A或DLA - B抗原，或两者均与供体不同的受体中进行皮肤移植，其平均存活时间（MST）分别为9.3天、9.7天和8.5天。这些组之间的差异不显著。然而，在SK - LD相同（MST：12.4天）或SD相同/LD不同（MST：12.5天）的供体 - 受体组合中发现皮肤移植存活时间延长。我们得出结论，犬类皮肤同种异体移植的存活似乎受DLA - A和DLA - B控制，但不受DLA - D决定簇控制。