Böhme M, Löttge M, Cuno-Klausenitz S
Hauptabteilung Gynäkologie, Klinik St. Marienstift Magdeburg.
Zentralbl Gynakol. 1995;117(4):217-9.
Two cases of Cystosarcomata phylloides (C. ph.) in the breast were reported. In the first one after excision of the palpaple tumour mass the histological examination revealed a fibroadenoma with signs of C. ph. in the excision margins. The reported high rate of local recurrence also in cases of benign tumour type and/or in situ remained tumour structures (stromal hyperplasia) gave the reason for a second operation procedure, an enlarged quadrantectomy. In the second case sarcomatic degenerated areas and a high rate of atypical mitotic figures were found (> 20 mitosis/10 HPF). Therefore an ablative surgery was recommended.