Mikhail M S, Anyaegbunam A, Romney S L
Department of Obstetrics & Gynecology, Albert Einstein College of Medicine, Bronx, New York, USA.
Acta Obstet Gynecol Scand. 1995 May;74(5):376-8. doi: 10.3109/00016349509024432.
Computerized colposcopy is the noninvasive digital processing of colposcopic images acquired using a charge-coupled device camera. The purpose of this study was to evaluate the clinical applications of computerized colposcopy, and to record the colposcopic changes associated with progression or regression of cervical intraepithelial neoplasia in pregnancy.
Forty-one pregnant patients, with abnormal Papanicolaou smears and a fully visualized squamo-columnar junction, were serially monitored throughout their pregnancies using computerized colposcopy. All patients had baseline computer-assisted measurements of their cervical lesions and a repeat measurement at monthly intervals and at 3-months postpartum.
During the period of gestation, 17.1% of lesions increased in size, 21.9% remained unchanged, 41.5% decreased in size and 19.5% disappeared completely. In patients with an increase in lesion size, a colposcopically directed punch biopsy was performed which revealed CIN III but no microinvasion. Cervical biopsy during pregnancy was unnecessary in 82.9% of cases.
The ability to sequentially monitor and quantify colposcopically visualized lesions, using computerized colposcopy, provides a noninvasive objective mode to evaluate progression, stability, or regression of CIN lesions during pregnancy.
计算机化阴道镜检查是对使用电荷耦合器件相机获取的阴道镜图像进行无创数字处理。本研究的目的是评估计算机化阴道镜检查的临床应用，并记录与妊娠期宫颈上皮内瘤变进展或消退相关的阴道镜变化。
41例巴氏涂片异常且鳞柱交界完全可见的孕妇在整个孕期使用计算机化阴道镜进行连续监测。所有患者在基线时对宫颈病变进行计算机辅助测量，并在每月以及产后3个月进行重复测量。
在妊娠期，17.1%的病变增大，21.9%保持不变，41.5%缩小，19.5%完全消失。对于病变增大的患者，进行了阴道镜引导下的穿刺活检，结果显示为CIN III但无微小浸润。82.9%的病例在孕期无需进行宫颈活检。
使用计算机化阴道镜对阴道镜下可见病变进行连续监测和量化的能力，为评估妊娠期CIN病变的进展、稳定或消退提供了一种无创的客观模式。
