Miettinen P V
Department of Anatomy, University of Kuopio, Finland.
Berl Munch Tierarztl Wochenschr. 1995 Jan;108(1):14-9.
To avoid a harmful peak of negative energy balance, 200 ml of a 50% propylene glycol and 1% nicotinic amide solution were given twice a day to dairy cattle for ten days starting at day 14 post partum (p.p). Acetone content in milk was used as an indicator of energy balance and fertility was used as an indicator of the efficiency of the treatment. In addition, other factors affecting fertility were evaluated. During the prevention period, the acetone level in the prevention group (N = 31) decreased from 0.40 +/- 0.1 O mmol/l to 0.23 +/- 0.06 mmol/l (p = 0.09), but in the control group (N = 35) it increased from 0.23 +/- 0.04 mmol/l to 0.43 +/- 0.29 mmol/l acetone from the beginning to the end of the trial (p > 0.10). At day 50 p.p., however, the acetone levels in the two groups were the same. The treatment did not prevent clinical ketosis. Clinical ketosis tended to be associated with impaired fertility; in contrast, cows in the prevention group treated for ketosis had high fertility. A high daily milk yield at the first monthly recording test as well as high annual milk, fat and protein yields were correlated with the interval from calving to conception, r = 0.33, r = 0.50, r = 0.37 and r = 0.47, respectively. A low percentage of annual milk protein and at test 1 was significantly correlated with a long interval from calving to conception, r=-0.31 and r=-0.45, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
为避免负能量平衡出现有害峰值，从产后第14天起，每天给奶牛两次200毫升50%丙二醇和1%烟酰胺溶液，持续10天。牛奶中的丙酮含量被用作能量平衡指标，繁殖力被用作治疗效果指标。此外，还评估了其他影响繁殖力的因素。在预防期，预防组（N = 31）的丙酮水平从0.40±0.10毫摩尔/升降至0.23±0.06毫摩尔/升（p = 0.09），但对照组（N = 35）在试验开始到结束时，丙酮水平从0.23±0.04毫摩尔/升升至0.43±0.29毫摩尔/升（p>0.10）。然而，在产后第50天，两组的丙酮水平相同。该治疗未能预防临床酮病。临床酮病往往与繁殖力受损有关；相比之下，接受酮病治疗的预防组奶牛繁殖力较高。首次月度记录测试时的高日产奶量以及高年奶量、脂肪产量和蛋白质产量与产犊至受孕间隔相关，r分别为0.33、0.50、0.37和0.47。年奶蛋白百分比低以及首次测试时的低水平与产犊至受孕的长间隔显著相关，r分别为-0.31和-0.45。（摘要截断于250字）
