1-脱氧甘露基野尻霉素是甘露糖苷酶II的非竞争性抑制剂。 - Suppr | 超能文献

1-Deoxymannojirimycin is a non-competitive inhibitor of mannosidase II.

作者信息

Slusarewicz P, Warren G

机构信息

Cell Biology Laboratory, Imperial Cancer Research Fund, London, UK.

出版信息

Glycobiology. 1995 Mar;5(2):154-5. doi: 10.1093/glycob/5.2.154.

DOI:10.1093/glycob/5.2.154

Abstract

摘要

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1-Deoxymannojirimycin is a non-competitive inhibitor of mannosidase II.1-脱氧甘露基野尻霉素是甘露糖苷酶II的非竞争性抑制剂。

Glycobiology. 1995 Mar;5(2):154-5. doi: 10.1093/glycob/5.2.154.

2

alpha-D-Mannosidases of rat liver Golgi membranes. Mannosidase II is the GlcNAcMAN5-cleaving enzyme in glycoprotein biosynthesis and mannosidases Ia and IB are the enzymes converting Man9 precursors to Man5 intermediates.大鼠肝脏高尔基体膜的α-D-甘露糖苷酶。甘露糖苷酶II是糖蛋白生物合成中切割GlcNAcMAN5的酶，而甘露糖苷酶Ia和IB是将Man9前体转化为Man5中间体的酶。

J Biol Chem. 1982 Apr 10;257(7):3660-8.

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Mannosidase IA from rat liver Golgi membranes.

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4

Asparagine-linked glycoprotein biosynthesis in rat epididymis. Presence of a mannosidase II-like enzyme.大鼠附睾中与天冬酰胺连接的糖蛋白生物合成。一种类甘露糖苷酶II的存在。

Biochem J. 1991 Jul 1;277 ( Pt 1)(Pt 1):213-21. doi: 10.1042/bj2770213.

5

alpha-D-Mannosidase from Golgi membranes of rat liver.

Methods Enzymol. 1978;50:500-5. doi: 10.1016/0076-6879(78)50052-9.

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Purification and characterization of alpha-D-mannosidase from rat liver golgi membranes.大鼠肝脏高尔基体膜中α-D-甘露糖苷酶的纯化与特性分析

J Biol Chem. 1977 May 25;252(10):3227-33.

7

Marked differences in the swainsonine inhibition of rat liver lysosomal alpha-D-mannosidase, rat liver Golgi mannosidase II, and jack bean alpha-D-mannosidase.苦马豆素对大鼠肝脏溶酶体α-D-甘露糖苷酶、大鼠肝脏高尔基体甘露糖苷酶II和刀豆α-D-甘露糖苷酶的抑制作用存在显著差异。

Arch Biochem Biophys. 1985 Jan;236(1):427-34. doi: 10.1016/0003-9861(85)90643-5.

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Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.基夫内新，一种强效的糖蛋白加工甘露糖苷酶I抑制剂。

J Biol Chem. 1990 Sep 15;265(26):15599-605.

9

The effect of 1-deoxymannojirimycin on rat liver alpha-mannosidases.1-脱氧甘露基野尻霉素对大鼠肝脏α-甘露糖苷酶的作用。

Biochem Biophys Res Commun. 1984 Nov 30;125(1):324-31. doi: 10.1016/s0006-291x(84)80371-x.

10

Comparison of kifunensine and 1-deoxymannojirimycin binding to class I and II alpha-mannosidases demonstrates different saccharide distortions in inverting and retaining catalytic mechanisms.对 kifunensine 和 1-脱氧甘露基野尻霉素与 I 类和 II 类 α-甘露糖苷酶结合的比较表明，在转化和保留催化机制中存在不同的糖扭曲。

Biochemistry. 2003 Dec 2;42(47):13812-6. doi: 10.1021/bi034742r.

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