Ray D, Saha K, Date A, Jairaj P S
Department of Chest Diseases, Christian Medical College, Vellore, India.
Ceylon Med J. 1995 Mar;40(1):14-8.
To study the serum IgE response in nonallergic subjects with chronic inflammatory lung diseases.
Christian Medical College Hospital, Vellore.
Twenty six patients with bronchiectasis, five with pulmonary mycosis referred from all over India and 30 healthy subjects.
Serum IgE value (determined by radioimmuno assay) above the upper limit of normal control range (136 to 948 iu/ml) was considered as raised level.
Of the 26 patients with bronchiectasis 13 had pyogenic infections, six had pulmonary tuberculosis; in six patients sputum culture was sterile while another patient had herpes zoster. Five cases of mycosis included one each of actinomycosis, aspergillosis, blastomycosis, cryptococcosis and nocardiasis. The serum IgE levels were raised in 20 (65%) of the 31 patients.
Associated bacterial, fungal and parasitic infections were probably responsible for inducing an hyper-IgE response in these non-allergic subjects.
研究患有慢性炎症性肺部疾病的非过敏受试者的血清IgE反应。
韦洛尔基督教医学院医院。
26例支气管扩张症患者、5例来自印度各地的肺真菌病患者以及30名健康受试者。
血清IgE值（通过放射免疫测定法测定）高于正常对照范围上限（136至948国际单位/毫升）被视为升高水平。
26例支气管扩张症患者中，13例有化脓性感染，6例有肺结核；6例患者痰培养无菌，另1例患有带状疱疹。5例真菌病包括放线菌病、曲霉菌病、芽生菌病、隐球菌病和诺卡菌病各1例。31例患者中有20例（65%）血清IgE水平升高。
相关的细菌、真菌和寄生虫感染可能是这些非过敏受试者诱导高IgE反应的原因。
