Watanabe M, Takahashi A, Murayama T, Mano K, Watanabe H
Department of Neurology, Nagoya University School of Medicine.
Rinsho Shinkeigaku. 1995 Jan;35(1):73-5.
We evaluated time relation among hematocrit (Ht), platelet aggregation (PA) and the onset of acute stage-cerebral infarction in 221 patients. Lacunar infarctions were likely to occur in the evening or at midnight. The elevated Ht value was frequently found in patients with infarctions occurring at midnight, suggesting that the elevation of blood viscosity has an intimate etiology to the onset. The decrease of PA was often found in those who suffered from their stroke while awake in the morning or at midnight, and frequently had been associated with elevated Ht in the latter patients. Decrease of PA is often reported during acute stage-cerebral infarction. Our results indicate that increased platelet aggregation may play an important role in developing cerebral infarction, especially in those who had onset of illness in the morning.
我们评估了221例患者的血细胞比容（Ht）、血小板聚集（PA）与急性脑梗死发病之间的时间关系。腔隙性梗死多在傍晚或午夜发生。午夜发生梗死的患者中常出现Ht值升高，提示血液粘度升高与发病有密切病因关系。PA降低常见于早晨或午夜清醒时发生卒中的患者，且后者常与Ht升高相关。急性脑梗死期间常报道PA降低。我们的结果表明，血小板聚集增加可能在脑梗死的发生中起重要作用，尤其是在早晨发病的患者中。
