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[男性乳腺癌。关于50例病例]

[Cancer of the breast in men. Apropos of 50 cases].

作者信息

el Hajjam M, Khaiz D, Benider A, Lakhloufi A, Abi F, Kahlain A, Bouzidi A

机构信息

Service de Chirurgie III, CHU Ibn Rochd, Casablanca, Maroc.

出版信息

J Chir (Paris). 1995 Mar;132(3):131-6.

PMID:7782385
Abstract

Breast cancer, rarely encountered in men, accounts for 0.2 to 1.5% of the cancer morbidity in men and 1 to 5.7% of all breast cancers. The aim of this work is to analyse the different epidemiological, therapeutic and outcome features of this disease in men using a retrospective multicentric approach to 50 cases reported in Casablanca from 1980 to 1992. The mean age of the patients was 60.6 years. No significant risk factor was found. The mean delay to consultation was 22.5 months. Diagnosis was made at an advanced stage as, the tumour was located behind the nipple in 98% of the cases and ulcerated in 52%. Laterality was almost identical. Invasive galactophoric adenocarcinoma was found in 86% of the cases. Treatment was usually Patey mastectomy with positive nodes in 84%. Complementary treatment included radiotherapy in 60%, chemotherapy in 36% and hormonotherapy in 1 case. Recurrence was observed in 71% of the patients who has achieved complete remission. Surviceal in evaluable cases was 59 and 25% at 2 and 5 years respectively. The results in this series was less satisfactory that it is generally reported in the literature which suggests the need for better codification and management.

摘要

男性乳腺癌较为罕见,占男性癌症发病率的0.2%至1.5%,占所有乳腺癌的1%至5.7%。本研究旨在采用回顾性多中心方法,分析1980年至1992年在卡萨布兰卡报告的50例男性乳腺癌患者的不同流行病学、治疗及预后特征。患者的平均年龄为60.6岁。未发现显著的危险因素。平均就诊延迟时间为22.5个月。由于肿瘤位于乳头后方的病例占98%,且52%的病例出现溃疡,故多在疾病晚期确诊。双侧发病率几乎相同。86%的病例为浸润性乳腺导管癌。通常采用帕蒂乳房切除术治疗,84%的病例有阳性淋巴结。辅助治疗包括60%的患者接受放疗,36%的患者接受化疗,1例患者接受激素治疗。在达到完全缓解的患者中,71%出现复发。可评估病例的2年和5年生存率分别为59%和25%。本系列研究结果不如文献中普遍报道的那样令人满意,这表明需要更好的编码和管理。

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