放疗治疗鞍上生殖细胞瘤后发生的异时性卵巢无性细胞瘤。病例报告。

Metachronous ovarian dysgerminoma after a suprasellar germ-cell tumor treated by radiation therapy. Case report.

作者信息

Watanabe T, Makiyama Y, Nishimoto H, Matsumoto M, Kikuchi A, Tsubokawa T

机构信息

Division of Neurological Surgery, Saitama Children's Medical Center, Japan.

出版信息

J Neurosurg. 1995 Jul;83(1):149-53. doi: 10.3171/jns.1995.83.1.0149.

DOI:10.3171/jns.1995.83.1.0149

PMID:7782834

Abstract

A case of suprasellar germ-cell tumor in a 9-year-old girl who later developed ovarian dysgerminoma is reported. The clinical course of the case is described and a double-primary tumor, rather than metastasis from either tumor to the other, is suggested by the authors to explain the oncogenesis in this patient. The authors strongly encourage that patients with intracranial germinoma be examined for associated extraneural lesions before, as well as after, the completion of the initial therapy.

摘要

报告了一例9岁女孩鞍上生殖细胞瘤病例，该女孩后来发展为卵巢无性细胞瘤。描述了该病例的临床病程，作者认为这是一种双原发性肿瘤，而非肿瘤之间的转移，以此来解释该患者的肿瘤发生机制。作者强烈建议，颅内生殖细胞瘤患者在初始治疗前和治疗后均应检查是否存在相关的神经外病变。