Nourani Mona, Manera Ricarchito B
*Department of Pediatric Hematology/Oncology †Division of Pediatric Hematology/Oncology, Loyola University Health Center, Maywood, IL.
J Pediatr Hematol Oncol. 2013 Oct;35(7):e272-3. doi: 10.1097/MPH.0b013e31829bcaf1.
Malignancy-associated hypercalcemia is a common finding among adult malignancies. However, the incidence of malignancy-induced hypercalcemia associated with germ cell tumor among pediatric patients is very rare. We describe a 9-year-old girl with an ovarian dysgerminoma presenting with chronic constipation and hypercalcemia. We review some of the causes of malignancy-associated hypercalcemia described in literature and treatment strategies. We also recommend considering oncological processes in the presence of hypercalcemia.
恶性肿瘤相关高钙血症在成人恶性肿瘤中很常见。然而，小儿患者中与生殖细胞肿瘤相关的恶性肿瘤诱发的高钙血症发病率非常低。我们描述了一名9岁患有卵巢无性细胞瘤的女孩，她表现为慢性便秘和高钙血症。我们回顾了文献中描述的一些恶性肿瘤相关高钙血症的病因及治疗策略。我们还建议在出现高钙血症时考虑肿瘤学相关情况。
