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多不饱和脂肪酸能预防氧化剂引起的肺损伤吗?

Do polyunsaturated fatty acids protect against oxidant-induced lung damage?

作者信息

Sosenko I R

机构信息

Department of Pediatrics, University of Miami School of Medicine, FL 33101, USA.

出版信息

J Nutr. 1995 Jun;125(6 Suppl):1652S-1656S. doi: 10.1093/jn/125.suppl_6.1652S.

Abstract

Little disagreement exists concerning the importance of early provision of lipid nutrition to very low birth weight (VLBW) infants in terms of growth and development. However, considerable controversy surrounds the relationship of lipid and protection against oxidant-induced lung damage in experimental situations and in the vulnerable premature infant. This article reviews the results of experimental and clinical studies on the protective effects of lipids against oxidant injury and chronic lung disease.

摘要

对于为极低出生体重(VLBW)婴儿尽早提供脂质营养在生长发育方面的重要性,几乎不存在分歧。然而,在实验情形以及脆弱的早产儿中,脂质与预防氧化应激诱导的肺损伤之间的关系存在相当大的争议。本文综述了关于脂质对氧化损伤和慢性肺病保护作用的实验及临床研究结果。

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