Isao H
Department of Otorhinolaryngology, Kitasato University, School of Medicine, Sagamihara.
Nihon Jibiinkoka Gakkai Kaiho. 1995 Apr;98(4):589-98.
When vestibular organs are abnormally stimulated, autonomic reactions such as nausea, vomiting, palpitation, etc., occur, indicating the existence of fiber connections from the vestibular organs to the autonomic centers. The relationship between the "vomiting center" in the medulla oblongata as described by Borison and Wang and the vestibular nucleus remains obscure. To investigate the central mechanism of vomiting caused by vestibular stimulation, the intragastric pressure, gastric peristalsis and respiration during electric stimulation of the medullary vomiting center and the semicircular canal nerve were recorded in 12 adult cats. Evoked potential was also recorded while electrically stimulating the semicircular canal nerve. When the peripheral labyrinth was stimulated, a conflicting result was founded, namely, that the pressure in the stomach increased or decreased. Retching or vomiting-like behavior was observed in several sites when the dorsolateral portion of the reticular formation of the medulla was stimulated. It was found that neural structures in the dorsolateral portion of the reticular formation of the medulla were associated with the semicircular canal nerve, but retching or vomiting-like behavior was not always observed during stimulation there.
当前庭器官受到异常刺激时，会出现恶心、呕吐、心悸等自主反应，这表明前庭器官与自主神经中枢之间存在纤维联系。博里森和王所描述的延髓“呕吐中枢”与前庭核之间的关系仍不明确。为了研究前庭刺激引起呕吐的中枢机制，对12只成年猫在电刺激延髓呕吐中枢和半规管神经时的胃内压、胃蠕动和呼吸进行了记录。在电刺激半规管神经时也记录了诱发电位。当刺激外周迷路时，得到了相互矛盾的结果，即胃内压升高或降低。当刺激延髓网状结构的背外侧部分时，在几个部位观察到干呕或类似呕吐的行为。发现延髓网状结构背外侧部分的神经结构与半规管神经有关，但在那里刺激时并不总是观察到干呕或类似呕吐的行为。
