Tatum W O, Zachariah S B
Department of Neurology, University of South Florida, Tampa, USA.
Neurology. 1995 Jun;45(6):1216-7. doi: 10.1212/wnl.45.6.1216.
Most antiepileptic drugs (AEDs) available have demonstrated porphyrogenicity in hepatic porphyrias. Gabapentin is a new AED not appreciably metabolized by the liver in humans. We report two patients with acute intermittent porphyria successfully treated with gabapentin without its inducing porphyric crisis.