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聚四氟乙烯尿道下吊带治疗真性压力性尿失禁的长期临床及尿动力学评估

Long-term clinical and urodynamic evaluation of the polytetrafluoroethylene suburethral sling for treatment of genuine stress incontinence.

作者信息

Weinberger M W, Ostergard D R

机构信息

Department of Obstetrics and Gynecology, University of California, Irvine, USA.

出版信息

Obstet Gynecol. 1995 Jul;86(1):92-6. doi: 10.1016/0029-7844(95)00098-C.

Abstract

OBJECTIVE

To assess long-term clinical and urodynamic outcomes of suburethral sling procedures using polytetrafluoroethylene grafts.

METHODS

Between January 1986 and May 1991, 108 women underwent suburethral sling placement to treat genuine stress incontinence. At least 1 year after surgery, 62 women participated in a telephone interview about surgical outcome and completed a follow-up urodynamic evaluation.

RESULTS

Seventy-three percent of patients reported stress incontinence cure and 61% were objectively cured. Neither low urethral closure pressure nor a history of multiple prior anti-incontinence procedures, singly or in combination, adversely affected outcome. Postoperative maximum urethral closure pressure and functional urethral length were significantly greater in patients who were cured of their incontinence than in those whose surgery failed. Patients who were cured had higher amplitude detrusor contractions during micturition and greater post-void residual urine than those who were not cured. Thirty-three percent of patients with urodynamically stable bladders preoperatively developed detrusor instability after surgery. Detrusor instability remitted after surgery in half of the patients who had this condition preoperatively. Postoperative wound complications developed in 40% of patients who underwent sling placement, and 22% of the grafts were eventually removed.

CONCLUSION

Polytetrafluoroethylene suburethral sling placement is an effective treatment for stress incontinence and low urethral pressure. Urodynamic data suggest that urethral obstruction is responsible for surgical cure. Patients should be warned of the high complication rate for this suburethral sling procedure and that graft removal may be necessary.

摘要

目的

评估使用聚四氟乙烯移植物的尿道下吊带手术的长期临床和尿动力学结果。

方法

1986年1月至1991年5月期间,108名女性接受了尿道下吊带置入术以治疗真性压力性尿失禁。术后至少1年,62名女性参与了关于手术结果的电话访谈并完成了随访尿动力学评估。

结果

73%的患者报告压力性尿失禁治愈,61%在客观上治愈。低尿道闭合压以及既往多次抗尿失禁手术史,单独或联合出现,均未对结果产生不利影响。尿失禁治愈的患者术后最大尿道闭合压和功能性尿道长度显著高于手术失败的患者。治愈的患者排尿时逼尿肌收缩幅度更高,残余尿量也比未治愈的患者更多。术前膀胱尿动力学稳定的患者中有33%术后出现逼尿肌不稳定。术前有此情况的患者中,半数术后逼尿肌不稳定症状缓解。接受吊带置入术的患者中有40%出现术后伤口并发症,最终22%的移植物被取出。

结论

聚四氟乙烯尿道下吊带置入术是治疗压力性尿失禁和低尿道压力的有效方法。尿动力学数据表明尿道梗阻是手术治愈的原因。应告知患者该尿道下吊带手术并发症发生率高,且可能需要取出移植物。

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