Giraudet-Le Quintrec J S, Peyrache M D, Courpied J P, Menkès C J, Kerboull M
Service d'Orthopédie, Groupe hospitalier Cochin, Paris.
Presse Med. 1995;24(15):719-21.
A case of massive osteolysis (disappearing bone disease, phantom bone, Gorham's massive osteolysis) was observed in a young african man with two lesions of the femur. This is a very rare syndrome characterized by an acute spontaneous resorption of bone, without any sign of malignant or infectious disorder. The lesion may develop in any part of the skeleton, with extensive bone loss, but is benign. Bone is replaced by haemangiomatous tissue. The diagnosis lead on the association of clinical, radiological and histological signs. The pathogenesis is still unknown and the treatment remains controversial. Osteolysis stops after a few years, but this is unpredictable; in our case, we have proposed prosthetic replacement, associated with bone grafting and irradiation.
一名患有双侧股骨病变的年轻非洲男性被诊断为大块骨质溶解症（消失性骨病、幽灵骨、戈勒姆大块骨质溶解症）。这是一种非常罕见的综合征，其特征是骨的急性自发性吸收，无任何恶性或感染性疾病迹象。该病变可发生于骨骼的任何部位，伴有广泛骨质流失，但为良性。骨被血管瘤组织替代。诊断基于临床、放射学和组织学征象的综合判断。其发病机制仍不清楚，治疗方法也存在争议。骨质溶解在数年后会停止，但这无法预测；在我们的病例中，我们建议进行假体置换，并结合骨移植和放疗。
