百草枯经皮肤吸收中毒所致的肺损伤

Pulmonary damage due to paraquat poisoning through skin absorption.

作者信息

Papiris S A, Maniati M A, Kyriakidis V, Constantopoulos S H

机构信息

Department of Internal Medicine, University of Ioannina, Greece.

出版信息

Respiration. 1995;62(2):101-3. doi: 10.1159/000196400.

DOI:10.1159/000196400

PMID:7784705

Abstract

A case of recovery from acute respiratory insufficiency due to paraquat is described. A 57-year-old farmer developed breathlessness, high fever and interstitial infiltrates in the upper and middle lung fields few days after percutaneous paraquat poisoning with rapid evolution to pulmonary fibrosis. Anti-inflammatory drugs and antioxidants, were administered to the patient, though with a delay, with some improvement; the patient survived despite residual lung fibrosis. Paraquat lung, as confirmed by this paper, is not invariably fatal.

摘要

本文描述了一例因百草枯中毒导致急性呼吸功能不全后康复的病例。一名57岁的农民在经皮百草枯中毒几天后出现呼吸困难、高热，上、中肺野出现间质浸润，并迅速发展为肺纤维化。尽管给药延迟，但给予了抗炎药和抗氧化剂，患者病情有所改善；尽管残留肺纤维化，患者仍存活。本文证实，百草枯肺并非必然致命。