[Practice-oriented treatment of depression today].

The modern treatment methods which are relevant for everyday practice are summarized, and their application is discussed based on an integrative depression model. The biological and psychosocial therapeutic methods can be complementary, if the actual stage of illness is taken into consideration. An antidepressive medication is needed, especially in severe depressive episodes. The application of some simple rules can assist in the choice of antidepressive medication. But also the employment of sound principles for the psychosocial treatment of depressive patients is recommended.