Traven N D, Kuller L H, Ives D G, Rutan G H, Perper J A
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA.
Am J Epidemiol. 1995 Jul 1;142(1):45-52. doi: 10.1093/oxfordjournals.aje.a117544.
Trends in coronary heart disease mortality and sudden death were studied in 35- to 44-year-old white male residents of Allegheny County, Pennsylvania. Deaths coded as any cardiac or vascular disease, diabetes, unexplained sudden death, and other rubrics were eligible for investigation, and the cause of death was validated by physicians examining multiple data sources about the deaths. During 1970-1990, 1,424 white male deaths were investigated, with 903 validated as coronary heart disease. In that time span, white male coronary heart disease mortality fell from 93.4 to 36.7 per 100,000 population per year, a 60% decline. Little proportionate change was seen in characteristics of the deaths, which were predominantly sudden and out-of-hospital. Diabetes mellitus history increased proportionately over time, largely because diabetics' mortality rates, unlike those of all other subgroups, did not fall. These observations support the contention that the decline in coronary heart disease mortality relates to risk factor modification more than to improvements in the treatment of coronary heart disease. Differences in death certification practices must be considered when interpreting and comparing vital statistics data.
对宾夕法尼亚州阿勒格尼县35至44岁的白人男性居民的冠心病死亡率和猝死趋势进行了研究。编码为任何心脏或血管疾病、糖尿病、不明原因猝死及其他类别的死亡均纳入调查范围,且死亡原因由医生通过查阅多源死亡数据进行验证。1970年至1990年期间,共调查了1424例白人男性死亡病例,其中903例被确认为冠心病死亡。在此期间,白人男性冠心病死亡率从每年每10万人中的93.4例降至36.7例,降幅达60%。死亡特征方面的比例变化不大,死亡主要为突然发生且在院外。糖尿病病史随时间呈比例增加,主要原因是与所有其他亚组不同,糖尿病患者的死亡率并未下降。这些观察结果支持以下观点,即冠心病死亡率的下降更多地与危险因素的改变有关,而非冠心病治疗的改善。在解释和比较生命统计数据时,必须考虑死亡认证做法的差异。