驱动蛋白中运动极性的决定因素。
Determinants of motor polarity in the kinesin proteins.
作者信息
Endow S A
机构信息
Department of Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
出版信息
Biophys J. 1995 Apr;68(4 Suppl):271S-274S.
Abstract
Many of the proteins that are members of the kinesin family of microtubule motor proteins are plus-end motors; however, a few of the kinesin proteins have now been found to be minus-end microtubule motors. Overall structural features of the proteins can be used to identify further kinesins that are likely to be minus-end motors. Structural or biochemical differences that may serve as the basis of the "reversed" polarity of a unique subset of the kinesin proteins are discussed.
摘要
许多作为微管运动蛋白驱动蛋白家族成员的蛋白质是正向末端运动蛋白；然而，现在已经发现一些驱动蛋白是负向末端微管运动蛋白。这些蛋白质的整体结构特征可用于进一步鉴定可能是负向末端运动蛋白的驱动蛋白。文中讨论了可能作为驱动蛋白独特亚群“反向”极性基础的结构或生化差异。
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