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Determinants of motor polarity in the kinesin proteins.驱动蛋白中运动极性的决定因素。
Biophys J. 1995 Apr;68(4 Suppl):271S-274S.
2
Structural features involved in force generation in the kinesin superfamily.驱动蛋白超家族中参与力产生的结构特征。
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Biophys J. 1995 Apr;68(4 Suppl):267S-269S; discussion 269S-270S.
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Highly processive motility is not a general feature of the kinesins.高持续性运动并非驱动蛋白的普遍特征。
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Switch-based mechanism of kinesin motors.驱动蛋白马达的基于开关的机制。
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Structural and functional features of one- and two-headed biotinated kinesin derivatives.单头和双头生物素化驱动蛋白衍生物的结构与功能特征
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引用本文的文献

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MAP/microtubule affinity-regulating kinases, microtubule dynamics, and spermatogenesis.MAP/microtubule affinity-regulating kinases，微管动力学和精子发生。
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2
Molecular motors and a spectrin matrix associate with Golgi membranes in vitro.分子马达和血影蛋白基质在体外与高尔基体膜相关联。
J Cell Biol. 1997 Dec 1;139(5):1169-81. doi: 10.1083/jcb.139.5.1169.
3
The shapes of the motor domains of two oppositely directed microtubule motors, ncd and kinesin: a neutron scattering study.两种反向微管马达蛋白ncd和驱动蛋白的马达结构域形状：一项中子散射研究
Biophys J. 1995 Oct;69(4):1563-8. doi: 10.1016/S0006-3495(95)80028-7.

本文引用的文献

1
Cytologic Studies on the Abnormal Development of the Eggs of the Claret Mutant Type of Drosophila Simulans.拟暗果蝇酒红色突变型卵子异常发育的细胞学研究
Genetics. 1936 May;21(3):264-81. doi: 10.1093/genetics/21.3.264.
2
Motor proteins. 1: kinesins.运动蛋白。1：驱动蛋白。
Protein Profile. 1994;1(10):1059-116.
3
Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd protein.微管运动方向是驱动蛋白重链和果蝇ncd蛋白的马达结构域的固有属性。
Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5209-13. doi: 10.1073/pnas.90.11.5209.
4
Identification of a gene family (kat) encoding kinesin-like proteins in Arabidopsis thaliana and the characterization of secondary structure of KatA.拟南芥中编码类驱动蛋白的基因家族（kat）的鉴定及KatA二级结构的表征
Mol Gen Genet. 1993 Apr;238(3):362-8. doi: 10.1007/BF00291995.
5
Structural and functional domains of the Drosophila ncd microtubule motor protein.果蝇ncd微管运动蛋白的结构域和功能域
J Biol Chem. 1993 Apr 25;268(12):9005-13.
6
Recombinant kinesin motor domain binds to beta-tubulin and decorates microtubules with a B surface lattice.重组驱动蛋白运动结构域与β-微管蛋白结合，并以B表面晶格装饰微管。
Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1671-5. doi: 10.1073/pnas.90.5.1671.
7
Cell motility. Variations on the theme of movement.细胞运动性。运动主题的变体。
Nature. 1993 Jan 14;361(6408):115-6. doi: 10.1038/361115a0.
8
Suppression of the bimC4 mitotic spindle defect by deletion of klpA, a gene encoding a KAR3-related kinesin-like protein in Aspergillus nidulans.通过缺失klpA（构巢曲霉中一个编码与KAR3相关的驱动蛋白样蛋白的基因）来抑制bimC4有丝分裂纺锤体缺陷。
J Cell Biol. 1993 Jan;120(1):153-62. doi: 10.1083/jcb.120.1.153.
9
Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region.一个位于人类主要组织相容性复合体（MHC）区域着丝粒末端的新的驱动蛋白相关基因的克隆。
Immunogenetics. 1994;39(3):194-200. doi: 10.1007/BF00241260.
10
The rate-limiting step in microtubule-stimulated ATP hydrolysis by dimeric kinesin head domains occurs while bound to the microtubule.二聚体驱动蛋白头部结构域在微管刺激下进行ATP水解的限速步骤发生在与微管结合时。
J Biol Chem. 1994 Jun 10;269(23):16508-11.

驱动蛋白中运动极性的决定因素。

Determinants of motor polarity in the kinesin proteins.

作者信息

Endow S A

机构信息

Department of Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

Biophys J. 1995 Apr;68(4 Suppl):271S-274S.

PMID:7787089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1281944/
Abstract

Many of the proteins that are members of the kinesin family of microtubule motor proteins are plus-end motors; however, a few of the kinesin proteins have now been found to be minus-end microtubule motors. Overall structural features of the proteins can be used to identify further kinesins that are likely to be minus-end motors. Structural or biochemical differences that may serve as the basis of the "reversed" polarity of a unique subset of the kinesin proteins are discussed.

摘要

许多作为微管运动蛋白驱动蛋白家族成员的蛋白质是正向末端运动蛋白；然而，现在已经发现一些驱动蛋白是负向末端微管运动蛋白。这些蛋白质的整体结构特征可用于进一步鉴定可能是负向末端运动蛋白的驱动蛋白。文中讨论了可能作为驱动蛋白独特亚群“反向”极性基础的结构或生化差异。