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[加蓬儿童疟疾特定治疗期间胆酶(5'-核苷酸酶和碱性磷酸酶)的变化]

[Variation of cholostase enzymes (5'-nucleotidase and alkaline phosphatase) during a specific treatment for malaria in the Gabonese child].

作者信息

Ngou-Milama E, Duong T H, Ozouaki P, Igwangou P, Kombila M

出版信息

Bull Soc Pathol Exot. 1995;88(1):15-7.

PMID:7787445
Abstract

Biological variations of 5'nucleotidase (5'NU) and alkaline phosphatase (AP) in 102 Gabonese children with malaria features (MF) and malaria infection (MI) receiving treatment are reported. [formula: see text] During the therapeutic assay, 5'NU rate decreases faster than AP'S; Fourteen days after the beginning of treatment, difference between AP MF and AP M1 is still significant. Enzymes decrease is an indication of the malaria drugs tolerance (MSP (*)).

摘要

报告了102名接受治疗的患有疟疾特征(MF)和疟疾感染(MI)的加蓬儿童中5'-核苷酸酶(5'NU)和碱性磷酸酶(AP)的生物学变化。[公式:见正文]在治疗试验期间,5'NU速率下降比AP的更快;治疗开始14天后,AP MF和AP M1之间的差异仍然显著。酶的下降是疟疾药物耐受性(MSP(*))的一个指标。

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