Gentry L O, Nasser M M, Kielhofner M
Infectious Disease Section, St. Luke's Episcopal Hospital, Houston, Texas 77030, USA.
Tex Heart Inst J. 1995;22(1):81-5.
Fungal endocarditis is rare and is usually caused by Aspergillus and Candida species. We present a patient with endocarditis caused by Scopulariopsis brevicaulis. The patient had a history of mitral valve disease and, 1 year earlier, had undergone valvuloplasty with the placement of a prosthetic Duran ring in the mitral valve position. S. brevicaulis was cultured from samples of a large vegetation on the mitral valve apparatus. The mitral valve was replaced with a St. Jude mechanical prosthesis. The patient was treated with amphotericin B but was later switched to oral itraconazole when antibiotic tests indicated susceptibility to that agent. We believe this is the 1st reported case of endocarditis caused by Scopulariopsis.
真菌性心内膜炎较为罕见，通常由曲霉菌和念珠菌属引起。我们报告一例由短帚霉引起的心内膜炎患者。该患者有二尖瓣疾病史，1年前接受了二尖瓣成形术，并在二尖瓣位置植入了人工杜兰环。从二尖瓣装置上一个大赘生物的样本中培养出了短帚霉。二尖瓣被置换为圣犹达机械瓣膜。患者接受了两性霉素B治疗，但后来当药敏试验表明对伊曲康唑敏感时，改为口服伊曲康唑治疗。我们认为这是首例报道的由短帚霉引起的心内膜炎病例。
